# Chrissy Metz Weight Loss on GLP-1: What She Said, What It Means

Source: https://www.dietglp.com/blog/chrissy-metz-glp-1-weight-loss/
Published: 2026-10-30
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**TL;DR:** Chrissy Metz, the "This Is Us" actress, said in August 2026 that she is taking a GLP-1 medication after years of doubt, and by fall 2026 outlets reported she had lost 63 pounds. She has not said publicly which drug she uses. She credits it with quieter "food noise," less joint pain and more stamina, and she started strength training with a trainer about a year before. That last part matters most: in trials, a real share of the weight lost on these drugs is lean mass, so [Sharpy](https://apps.apple.com/us/app/glp-diet-app-sharpy/id6762084138) gives you one protein target and one 20-minute workout a day to keep the loss coming from fat.

People searching "Chrissy Metz weight loss" want two things: what she actually said about her GLP-1, and whether the results are real. Short answer: the "This Is Us" star said in August 2026 that she is taking a GLP-1 medication after years of saying she never would. By fall 2026, Hello! and The Daily Beast reported she had lost 63 pounds. She has not named the drug. And the habit she paired it with, strength training with a trainer, is the part most people skip.

## Chrissy Metz GLP-1 timeline

| Date | What happened | Source |
|---|---|---|
| About mid-2025 | Starts strength training with a trainer (TODAY says "a year ago" in August 2026) | TODAY / NBC |
| August 10, 2026 | Tells TODAY she is on a GLP-1 and has partnered with telehealth company Ro | TODAY / NBC |
| June to September 2026 | Performs eight shows a week in "& Juliet" on Broadway | The Daily Beast |
| September 24, 2026 | Hello! reports she has lost 63 pounds since starting | Hello! |
| October 20, 2026 | Talks about food noise and her body at an Apple TV+ premiere in New York | The Daily Beast |
| October 27, 2026 | The Daily Beast publishes the interview; searches spike | The Daily Beast |

Two cautions before going further. First, her Ro partnership means her story is part of a public brand relationship. Second, one older headline says she "lost 100 pounds." That was years ago, at around age 30, on a diet and daily walking plan. It is not the GLP-1 number.

## Why Chrissy Metz was skeptical of GLP-1

She told TODAY she was "wary at first" and did not want to start something just because friends were. She had tried diets and therapy before and said none of it really worked for her. Two things changed her mind: a friend who described real benefits, and watching her father deal with obesity-related health problems. She saw a chance to "get ahead of it." Her doctors signed off before she began.

Her line that sums it up, per TODAY: "If nothing changes, nothing changes."

## Chrissy Metz GLP-1 benefits she describes

Here is what she has said, and what research says about each point. Her words are her experience, not proof.

| What she reports | What the evidence says |
|---|---|
| Less "food noise," fewer thoughts about food | GLP-1 drugs act on appetite centers in the brain and lower hunger. "Food noise" is not a medical term, but many users describe it this way. |
| Less joint pain and inflammation, better mobility | In the STEP 9 trial (NEJM, 2024), people with obesity and knee osteoarthritis on semaglutide 2.4 mg lost 13.7% of body weight vs 3.2% on placebo, and their knee pain score dropped more (41.7 vs 27.5 points). |
| A more regular menstrual cycle | Weight loss can affect cycles, especially in PCOS. GLP-1 drugs are not approved to treat cycle problems. Ask your doctor. |
| Stamina for eight shows a week | No trial measures this directly. Lower body weight usually makes daily movement easier. |
| Costumes needed to be altered | Her measurements changed. Inches often move before or faster than the scale. |

She also told The Daily Beast she is perimenopausal and has knee issues. She did not say the drug caused them.

## The part of her routine most people skip: lifting

According to TODAY, Metz started strength training with a trainer about a year before she went public, and she called it a critical choice as she enters perimenopause. That is the right instinct.

When you lose weight fast, you do not lose only fat. Body scans in the big trials show this:

| Trial | Drug | Average weight change | What the body scans showed |
|---|---|---|---|
| STEP 1 (NEJM, 2021) | Semaglutide 2.4 mg | -14.9% at 68 weeks | About 39% to 40% of the measured fat-plus-lean tissue lost was lean mass |
| SURMOUNT-1 (NEJM, 2022) | Tirzepatide 15 mg | -20.9% at 72 weeks | Fat mass fell 33.9%, lean mass 10.9%; about 75% of the loss was fat, 25% lean |

Lean mass is not all muscle. It also includes water and organs. But muscle is the part you can protect, and the two levers are simple: enough protein and regular resistance training. Our guide on [how much protein you need on a GLP-1](/blog/protein-target-on-glp1/) gives the numbers, and [strength training for women on GLP-1](/blog/glp1-and-women-strength/) explains why heavier lifting matters, especially in midlife.

This is exactly what [Sharpy](https://apps.apple.com/us/app/glp-diet-app-sharpy/id6762084138) is built for. You get one daily protein target, one 20-minute workout and one Shape Score, so you can see whether your loss is coming from fat rather than muscle.

## Perimenopause, GLP-1 and muscle

Metz is in her mid-40s and has said she is perimenopausal. Falling estrogen makes it harder to hold on to muscle and bone. Add a medication that cuts appetite, and protein can drop without you noticing. If that sounds like you:

- Eat protein first at each meal, before the rest of the plate.
- Lift two to three times a week with movements that get heavier over time.
- Track [your strength numbers](/blog/glp1-and-strength-numbers/), not just the scale.
- Talk to your doctor about hormones and bone health. Our [GLP-1 and menopause guide](/blog/glp1-and-menopause/) covers what to ask.

## Can you lose weight like Chrissy Metz on a GLP-1?

Celebrity numbers are one person. The trial averages above are the better guide, and people vary a lot in both directions. Some practical points:

- **Approved options.** Wegovy (semaglutide) and Zepbound (tirzepatide) are FDA approved for chronic weight management in adults with obesity, or overweight with at least one weight-related condition. Ozempic and Mounjaro are approved for type 2 diabetes.
- **Who decides.** Whether a GLP-1 fits you, which one and what dose is a decision for you and your prescriber. Telehealth companies, including the one Metz partners with, are one route. Your regular doctor is another.
- **Side effects.** Nausea, diarrhea, constipation and vomiting are the most common on the labels. Read our [Ozempic weight loss guide](/blog/ozempic-weight-loss-guide/) for how people manage the first months.
- **Pregnancy, eating disorder history, or under 18.** Talk to a doctor first. Do not start on your own.

## Bottom line

Chrissy Metz's story is real and widely reported: a longtime skeptic who started a GLP-1 in 2026 and has lost about 63 pounds, with less food noise and fewer aches. The detail worth copying is not the drug. It is that she was lifting with a trainer before she started. If you are on a GLP-1, make muscle the priority while the scale moves. [Sharpy](https://apps.apple.com/us/app/glp-diet-app-sharpy/id6762084138) keeps that simple: one protein number, one 20-minute workout and one Shape Score a day.

## Sources

- [Chrissy Metz reveals GLP-1 use, TODAY via NBC4 Washington, August 10, 2026](https://www.nbcwashington.com/entertainment/entertainment-news/chrissy-metz-reveals-glp-1-use/4140631/)
- [Chrissy Metz reveals unexpected GLP-1 side effect, The Daily Beast, October 27, 2026](https://www.thedailybeast.com/chrissy-metz-reveals-unexpected-glp-1-side-effect-after-60-lb-weight-loss)
- [Inside Chrissy Metz's weight-loss transformation, Hello!, September 24, 2026](https://www.hellomagazine.com/us/925148/inside-chrissy-metz-weight-loss-transformation-from-childhood-struggles-to-her-glp-1-journey/)
- [Bliddal et al. Once-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis (STEP 9), N Engl J Med 2024;391:1573-83, via Novo Nordisk](https://www.novonordisk-us.com/media/news-archive/news-details.html?id=171970)
- [STEP 1 trial record, ClinicalTrials.gov NCT03548935](https://clinicaltrials.gov/study/NCT03548935)
- [Body composition with tirzepatide in SURMOUNT-1, Diabetes Obes Metab 2025 (PMC11965027)](https://pmc.ncbi.nlm.nih.gov/articles/PMC11965027/)


## Frequently asked questions

**Q: How much weight has Chrissy Metz lost on a GLP-1?**

A: Hello! magazine (September 24, 2026) and The Daily Beast (October 27, 2026) both report that she has lost 63 pounds since starting a GLP-1. Some headlines round this to 60. No timeframe was given. A separate, older story about her losing 100 pounds at around age 30 was diet and walking, not a GLP-1.

**Q: What GLP-1 is Chrissy Metz taking?**

A: She has not named it in any interview we could find. Coverage only says "GLP-1 medication." Articles that mention Ozempic, Wegovy or Zepbound use them as general examples, not as her drug.

**Q: Is Chrissy Metz working with Ro?**

A: Yes. TODAY reported on August 10, 2026 that she has partnered with Ro, a telehealth company that prescribes medications such as GLP-1s. Keep that in mind when you read her story: it is a public partnership, not an independent review.

**Q: What benefits does Chrissy Metz say she gets from GLP-1?**

A: She describes less "food noise," less inflammation and joint pain, better mobility, a more regular menstrual cycle and the stamina to do eight shows a week on Broadway in "& Juliet." These are her own reports, not study results.

**Q: Why was Chrissy Metz skeptical of GLP-1 drugs?**

A: She said she did not want to do something just because friends were doing it, and that diets and therapy had not worked for her before. A friend describing real benefits and her father's obesity-related health problems changed her mind, and her doctors signed off first.

**Q: Does Chrissy Metz do strength training?**

A: Yes. According to TODAY, she began strength training with a trainer about a year before her August 2026 interview, and she called it a critical choice as she enters perimenopause.

**Q: Can I get the same results as Chrissy Metz?**

A: Nobody can promise that. In the big trials, the average was about 15% of body weight on semaglutide 2.4 mg (STEP 1) and about 21% on tirzepatide 15 mg (SURMOUNT-1), with wide ranges between people. Whether a GLP-1 is right for you is a decision for you and your prescriber.